Lupus & antiphospholipid syndrome

Epidemiology and outcomes of emergency department visits in systemic lupus erythematosus: Insights from the nationwide emergency department sample (NEDS)

LupusPublished Cross-sectional study

Authors' conclusion

Infection and SLE/CTD were among the top diagnoses associated with ED visits and inpatient admission. Despite comprising a significant proportion of SLE ED visits, Black patients had lower odds of admission.

Study context

Population
Adult (≥ 18 years) emergency department (ED) visits in the Nationwide Emergency Department Sample, 2019Systemic lupus erythematosus (SLE) ED visits (0.35%)
Participants
414,139 participants
Exposure
SLE ED visits vs non-SLE ED visits
  • SLEn = 414,139
Outcome
Epidemiology and outcomes of ED visits in SLE; factors associated with inpatient admission
Methodological detailsnationwide database (NEDS 2019), logistic regression
  • Nationwide database (NEDS 2019)
  • Logistic regression

Main finding

As reported in the abstract

Factors associated with inpatient admission among SLE ED visits

Odds ratio

0.86

P = 0.01

Black race

Odds ratio

0.78

P = 0.003

Lowest income quartile

Observational data: associations, not effects.

Further findings

Characteristics of SLE vs non-SLE ED visits

SLE ED visits comprised more women, Black patients, ages 31-50 years, Medicare as primary payer, and higher comorbidity burden

Youngest age category (18-30 years) by race among SLE ED visits

Black and Hispanic patients
around 20%
White patients
less than 10%

Medicaid utilization by race

Non-White patients
27%-32%
White patients
19%

Comorbidity patterns by race

More White patients with hyperlipidemia and ischemic heart disease (IHD); more Black patients with chronic kidney disease (CKD), hypertension and HF

Most prevalent primary ED diagnosis by race

SLE/CTD in non-White patients; infection in White patients

Original publication

Epidemiology and outcomes of emergency department visits in systemic lupus erythematosus: Insights from the nationwide emergency department sample (NEDS). Lupus. Published 14 November 2023. doi:10.1177/09612033231215381

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