Lupus & antiphospholipid syndrome
Burden of lupus activity on health care resources utilization in Buenos Aires, Argentina
Authors' conclusion
Significantly more HCRU was observed in patients with SLE in flare compared to remission periods.
Study context
- Population
- Patients with SLE from an health management organization (HMO) in Buenos Aires, Argentina, and matched controls; 88.7% women, median age at diagnosis 46 yearsfollowed >8 years
- Participants
- 62 vs 310
- Exposure
- SLE vs matched controls; flare vs remission periods
- SLEn = 62
- Controlsn = 310reference
- Outcome
- HCRU (consultations, lab and imaging tests, ED visits, hospitalizations, drugs prescribed), SLE vs controls and by activity state
Methodological detailsmatched controls (5 per case), health management organization, negative binomial regression
- Matched controls (5 per case)
- Health management organization
- Negative binomial regression
Main finding
As reported in the abstract
HCRU, SLE vs controls
- Health care resource utilization (HCRU) significantly higher in SLE than in controls in all items, even in remission periods
- HCRU significantly higher during flare periods vs remission periods
Observational data: associations, not effects.
Further findings
Follow-up time (patient-years)
Proportion of time in each activity state (SLE)
- Remission
- 74.4%
- LLDAS
- 12.1%
- Intermediate activity
- 12.2%
- Flare
- 1.3%
- Flares (64 flares in 36 patients)
Variables associated with major resource use
- Number of flares independently associated with ED consultations, lab tests and X-ray, number of drugs prescribed, and hospitalizations
Original publication
Burden of lupus activity on health care resources utilization in Buenos Aires, Argentina. Lupus. Published 13 November 2023. doi:10.
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