Spondyloarthritis & psoriatic arthritis
Enthesitis indices identify different patients with this characteristic in axial and peripheral spondyloarthritis and also in psoriatic arthritis: ASAS-PerSpA data
Authors' conclusion
These results suggest that the prevalence of patients with enthesitis across SpA subtypes differs depending on the disease and the index used.
Study context
- Population
- Patients with axial spondyloarthritis (axSpA), peripheral SpA (pSpA) or psoriatic arthritis (PsA) from the international cross-sectional ASAS-PerSpA study2,719 axSpA, 433 pSpA, 1033 PsA
- Participants
- 4,185 patients
- Exposure
- MEI vs MASES vs SPARCC index vs LEI for detecting enthesitis across axSpA, pSpA and PsA
- Outcome
- Proportion of patients with at least one enthesitis according to each index, and agreement among indices (Cohen's kappa)
Methodological detailsinternational, secondary analysis of ASAS-PerSpA data
- International
- Secondary analysis of ASAS-PerSpA data
Main finding
As reported in the abstract
Prevalence of ≥1 enthesitis by index (total population)
Observational data: associations, not effects.
Further findings
| Outcome | MEI | MASES | SPARCC | Kappa |
|---|---|---|---|---|
| Patients with enthesitis identified, axSpA (most identifying indices) | 98.7% | 82.4% | — not stated in the abstract | |
| Patients with enthesitis identified, pSpA (most identifying indices) | 100% | — not stated in the abstract | 84.6% | |
| Patients with enthesitis identified, PsA (most identifying indices) | 97.3% | — not stated in the abstract | 77% | |
| Agreement between indices (strongest pair), by populationMASES vs MEI · total population; absolute agreement 96.3% | 0.86 | |||
| Agreement between indices (strongest pair), by populationMASES vs MEI · axSpA; absolute agreement 97.3% | 0.90 | |||
| Agreement between indices (strongest pair), by populationSPARCC vs MEI · pSpA; absolute agreement 97.2% | 0.90 | |||
| Agreement between indices (strongest pair), by populationSPARCC vs MEI · PsA; absolute agreement 95.4% | 0.83 |
— not stated in the abstract
Original publication
Enthesitis indices identify different patients with this characteristic in axial and peripheral spondyloarthritis and also in psoriatic arthritis: ASAS-PerSpA data. Arthritis Res Ther. Published 8 June 2023. doi:10.
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