Lupus & antiphospholipid syndrome
Study of electrocardiographic corrected QT interval and QT dispersion abnormalities, erythrocyte sedimentation rate, serum uric acid in patients with systemic lupus erythematosus
Main finding · QTc valuesResult — go to the resultt 8.117Authors' conclusion
QTc interval and ESR values can be a simple and potential method for early detection of cardiac involvement in SLE patients with active disease activity.
Study context
- Population
- Systemic Lupus Erythematosus (SLE) patients and controls from general medicine and rheumatology outpatient department
- Participants
- 80 patients
- Comparison
- SLE patients vs controls
- SLEn = 40
- Controlsn = 40reference
- Outcome
- QTc values
Methodological detailsDuration 16 months, QTc by Bazett's method; ESR by Westergren's method; serum uric acid by automated analyzer
- Duration 16 months
- QTc by Bazett's method; ESR by Westergren's method; serum uric acid by automated analyzer
Main finding
As reported in the abstract
t
8.117
p-.0005
Observational data: associations, not effects.
Further findings
Correlation of ESR with SLEDAI among SLE patients
- ESR moderately correlated with SLEDAI (r)
- 0.460
- P
- p- .003
SELENA-SLEDAI disease activity in SLE patients
- Very high activity
- 40%
- High activity
- 40%
SLE duration 1–12 months
- Proportion
- 62.5%
Original publication
Study of electrocardiographic corrected QT interval and QT dispersion abnormalities, erythrocyte sedimentation rate, serum uric acid in patients with systemic lupus erythematosus. Lupus. Published 18 August 2024. doi:10.
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