Effect of research participation versus usual clinical care in patients with rheumatic and musculoskeletal disorders: a prospective cohort study
Authors' conclusion
Among musculoskeletal pain patients, research participants report more positive IP and better HR-QoL than non-participants. No additional effect of research participation was found in any outcome over time.
Study context
- Population
- Patients with musculoskeletal pain visiting the Outpatient Osteoarthritis Clinic at Frederiksberg Hospital, Copenhagen, 2019–2021
- Participants
- 1,495 patients
- Exposure
- Research participants vs non-participants
- Exposedn = 358
- Unexposedn = 1,137reference
- Outcome
- Change from baseline to follow-up in Brief Pain Inventory - Short Form (BPI-SF) item 'Average pain'
- Follow-up
- 10-18 months
Main finding
As reported in the abstract
Change in BPI-SF 'Average pain', baseline to follow-up
Mean BPI-sf Average pain between-group difference
−0.01 points
95% CI −0.6 to 0.6
Observational data: associations, not effects.
Secondary outcomes
Baseline Brief Illness Perception Questionnaire (B-IPQ) item scores
- Generally more favourable in exposed group; statistically significant standardised differences
- 0.2-0.3
Baseline EQ-5D-3L score (health-related quality of life (HR-QoL))
- Better HR-QoL in exposed group; standardised difference
- 0.3
Other outcomes over time
- Similar clinically irrelevant differences
Original publication
Effect of research participation versus usual clinical care in patients with rheumatic and musculoskeletal disorders: a prospective cohort study. RMD Open. Published 4 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →