Effect of isometric quadriceps exercise on local microcirculation of the infrapatellar fat pad in female patients with knee osteoarthritis
Authors' conclusion
During IQE, changes in hardness and hemoglobin concentration in the IFP were not significant in the KOA group, suggesting impaired local microcirculation of the IFP.
Study context
- Population
- Female patients with bilateral knee OA, healthy older adults and younger adultsknees per group
- Exposure
- Knee OA vs healthy older adults vs younger adults
- Knee osteoarthritis (KOA)n = 30 knees
- Controln = 20 kneesreference
- Youngn = 20 knees
- Outcome
- Changes in IFP hardness (shear wave velocity, US) and hemoglobin concentration (O2Hb, HHb, cHb; near-infrared spectroscopy) during isometric quadriceps exercise
Methodological detailsobservational, linear mixed model
- Observational
- Linear mixed model
Main finding
As reported in the abstract
IFP hardness change during isometric quadriceps exercise (IQE)
- Infrapatellar fat pad (IFP) hardness changes significantly less in KOA than in the other groups
Observational data: associations, not effects.
Further findings
Oxygenated hemoglobin (O2Hb) concentration change, Post vs Baseline · Post
- No significant O2Hb change in KOA; significant changes in the other groups
Original publication
Effect of isometric quadriceps exercise on local microcirculation of the infrapatellar fat pad in female patients with knee osteoarthritis. Osteoarthritis Cartilage. Published 31 May 2024. doi:10.
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