Effect of exercise training on heath, quality of life, exercise capacity in juvenile idiopathic arthritis: a meta-analysis of randomized controlled trials
Pooled result · Health (Child Health Assessment Questionnaire, CHAQ)Result — go to the resultSMD −0.32 95% CI −0.83 to 0.19Authors' conclusion
Exercise does not significantly affect the quality of life and exercise capacity in JIA patients but may relieve pain.
Study context
- Population
- Individuals with juvenile idiopathic arthritis (JIA); Randomized controlled trials (RCTs) from Medline, Embase, Web of Science and Cochrane Library, inception to October 20235 RCTs
- Comparison
- Exercise training in JIA
- Outcome
- Effect of exercise on health, quality of life and exercise capacities
Methodological detailsrandom or fixed effects models, Cochrane risk of bias tool, Grading of Recommendations Assessment, Development, and Evaluation (GRADE), Quality of evidence by GRADE moderate to very low
- Random or fixed effects models
- Cochrane risk of bias tool
- GRADE
- Quality of evidence by GRADE moderate to very low
Pooled result
As reported in the abstract
Health (Child Health Assessment Questionnaire, Child Health Assessment Questionnaire (CHAQ))
SMD
−0.32
95% CI −0.83 to 0.19
P = 0.011
Exercise
SMD −0.32 (95% CI −0.83 to 0.19); P = 0.011
Further pooled results
Quality of Life (QoL)
| SMD (95% CI) | P value | ||
|---|---|---|---|
| ExerciseHeterogeneity I2 = 29.4%; no significant effect | 0.27 (−0.04 to 0.58) | P = 0.243 | |
| −0.500.51Difference (linear scale) |
| Outcome | SMD (95% CI) | P value |
|---|---|---|
| VAS pain scores | 0.50 (−0.90 to −0.10) | P = 0.134 |
- Visual analog scale (VAS) pain scores: heterogeneity I2 = 50.2%; exercise significantly reduced pain
Peak oxygen uptake (VO2peak)
- No significant effect on VO2peak
Original publication
Effect of exercise training on heath, quality of life, exercise capacity in juvenile idiopathic arthritis: a meta-analysis of randomized controlled trials. Pediatr Rheumatol Online J. Published 4 March 2024. doi:10.
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