Pediatric rheumatology

Early-life dietary patterns and the risk of juvenile-onset ankylosing spondylitis: a nationwide cohort study in South Korea

Rheumatology (Oxford)Published Retrospective cohort study

Main finding · JASResult — go to the resultAdjusted hazard ratio 0.53 95% CI 0.31–0.90

Authors' conclusion

Paediatrics with high food diversity who were breastfed showed reduced vulnerability to JAS.

Study context

Population
Infants from the South Korean National Health Insurance Service
Participants
1,242,257 infants
Exposure
Early-life exposures and JAS incidence
Outcome
Incidence of juvenile-onset ankylosing spondylitis (JAS)
Methodological detailsnationwide, Cox proportional hazards models, subgroup analyses by food diversity level
  • Nationwide
  • Cox proportional hazards models
  • Subgroup analyses by food diversity level

Main finding

JAS

Adjusted hazard ratio

0.53

95% CI 0.31–0.90

P = 0.0195

Breastfeeding in infants with high food diversity
aHR 0.53 (95% CI 0.31–0.90); P = 0.0195

As reported in the abstract

Observational data: associations, not effects.

Original publication

Early-life dietary patterns and the risk of juvenile-onset ankylosing spondylitis: a nationwide cohort study in South Korea. Rheumatology (Oxford). Published 17 August 2026. doi:10.1093/rheumatology/keag433

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