Spondyloarthritis & psoriatic arthritis
Doppler Signal and Bone Erosions at the Enthesis Are Independently Associated With Ultrasound Joint Erosive Damage in Psoriatic Arthritis
Authors' conclusion
PD signal and bone erosions at the enthesis represent sonographic biomarkers of a more severe subset of PsA in terms of US-detected joint erosive damage.
Study context
- Population
- Consecutive patients with psoriatic arthritis (PsA); bilateral ultrasound (US) of plantar fascia and quadriceps, patellar (proximal and distal) and Achilles tendon entheses
- Participants
- 104 patients
- Outcome
- Association of OMERACT US entheseal abnormalities with US joint bone erosions
Methodological detailsconsecutive patients, multiple linear regression
- Consecutive patients
- Multiple linear regression
Main finding
As reported in the abstract
Variables associated with US-detected joint bone erosions (multivariate model)
Power Doppler (PD) signal at the enthesis, standardized β (P < 0.001)
0.51
Bone erosions at the enthesis, standardized β (P = 0.02)
0.20
PsA disease duration, standardized β (P = 0.04)
0.17
Greyscale joint synovitis, standardized β (P = 0.03)
0.42
Observational data: associations, not effects.
Further findings
At least 1 joint bone erosion (prevalence)
- 47 of 104 patients
- 45.2%
Bone erosions at fifth metatarsophalangeal (MTP) joint (most frequent site)
- 42/208 joints
- 20.2 %
- 32/104 patients
- 30.8%
Original publication
Doppler Signal and Bone Erosions at the Enthesis Are Independently Associated With Ultrasound Joint Erosive Damage in Psoriatic Arthritis. J Rheumatol. Published 1 February 2022. doi:10.
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