Spondyloarthritis & psoriatic arthritis

Do quality of life and work productivity change in early axial spondyloarthritis and non-axial spondyloarthritis patients after 2 years?

Rheumatology (Oxford)Published Prospective cohort study

Authors' conclusion

HRQoL and work productivity are more impaired in non-axSpA (vs axSpA) at baseline and also after 2 years. Although most outcomes improve in both groups, axSpA is associated with larger reductions in WPL and AI.

Study context

Population
Patients with chronic back pain of <2 years in the SPondyloArthritis Caught Early cohort
Participants
265 vs 108
Exposure
Axial SpA (axSpA) vs non-axSpA
  • axSpAn = 265
  • non-axSpAn = 108reference
Outcome
Health-related quality of life (HRQoL) (SF-36 PCS and MCS) and work productivity (WPAI presenteeism, absenteeism, WPL, AI)
Follow-up
2 years
Methodological detailsSPondyloArthritis Caught Early cohort, adjusted for baseline value, sex, age and NSAID use
  • SPondyloArthritis Caught Early cohort
  • Adjusted for baseline value, sex, age and NSAID use

Main finding

As reported in the abstract

Work productivity loss and activity impairment, multivariable analysis
axSpA vs non-axSpAIncidence rate ratio (95% CI)
WPL; 22% less WPL
0.78(0.62–0.98)
AI; 18% less AI
0.82(0.69–0.97)

Observational data: associations, not effects.

Further findings

Baseline presenteeism

Baseline absenteeism

Baseline WPL

Baseline AI

Mean

OutcomeaxSpAnon-axSpA
Baseline PCS, mean28.626.6

Baseline mental component summary (MCS)

MCS was not impaired in either group

Original publication

Do quality of life and work productivity change in early axial spondyloarthritis and non-axial spondyloarthritis patients after 2 years? Rheumatology (Oxford). Published 27 June 2024. doi:10.1093/rheumatology/keae346

Composed by AI from the published abstract and checked against it. How Briefs are made →

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