Spondyloarthritis & psoriatic arthritis
Change in different classes of chronic back pain suspicious of axial spondyloarthritis: a latent transition analysis of the SPACE cohort
Authors' conclusion
Transitions between the four classes over 2 years were basically inexistent, highlighting the unlikelihood of developing new class-defining features of axSpA after an initial clinical workup.
Study context
- Population
- Participants with chronic back pain of ≤2 years duration, suspicious of axial spondyloarthritis (axSpA), SPACE cohort384 with complete data
- Participants
- 702 participants
- Exposure
- Axial vs Inflammatory back pain+peripheral vs axSpA at risk vs No SpA
- Outcome
- Participants' transitions between the four classes over time
- Follow-up
- 2 years
Methodological detailslatent class analysis, latent transition analysis, imputation for missing data, sensitivity analysis in complete cases
- Latent class analysis
- Latent transition analysis
- Imputation for missing data
- Sensitivity analysis in complete cases
Main finding
As reported in the abstract
Class transitions, baseline to 2 years
Transition from 'no SpA' to 'at-risk' class
3%
Observational data: associations, not effects.
Further findings
Sensitivity analysis, complete data at baseline and 2 years
- Similar results, underlining the model's robustness
- 384 participants
Original publication
Change in different classes of chronic back pain suspicious of axial spondyloarthritis: a latent transition analysis of the SPACE cohort. RMD Open. Published 30 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →