Spondyloarthritis & psoriatic arthritis

Impact of pregnancy on sacroiliac imaging in women with axial spondyloarthritis: results of the analysis of the DESIR cohort

Scand J RheumatolPublished Prospective cohort study

Authors' conclusion

Following axSpA patients who had their first delivery showed a mild increase in left sacroiliitis on X-ray after delivery, but without other signs of structural or inflammatory aggravation on imaging.

Study context

Population
Women with early axial spondyloarthritis (axSpA) from the French prospective cohort DESIR38 with first delivery
Exposure
Nulliparous vs other women with axSpA; Sacroiliac joint (SIJ) imaging before vs after first delivery
Outcome
Impact of delivery on SIJ imaging
Methodological details5-year follow-up
  • 5-year follow-up

Main finding

As reported in the abstract

Change in SIJ imaging after first delivery (38 women nulliparous at baseline)
  • Only the modified New York score on the left SIJ was statistically different after delivery

Observational data: associations, not effects.

Further findings

Sacroiliitis on MRI at baseline

Sacroiliitis on X-ray at baseline

Women with first delivery vs nulliparous at end of follow-up

More sacroiliitis on X-ray and magnetic resonance imaging (MRI) at baseline, but lower Ankylosing Spondylitis Disease Activity Score-C-reactive protein (ASDAS-CRP)

Original publication

Impact of pregnancy on sacroiliac imaging in women with axial spondyloarthritis: results of the analysis of the DESIR cohort. Scand J Rheumatol. Published 19 June 2024. doi:10.1080/03009742.2024.2361993

Composed by AI from the published abstract and checked against it. How Briefs are made →

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