Spondyloarthritis & psoriatic arthritis
Do Patients Diagnosed With Psoriatic Arthritis Before or Concurrently With Psoriasis Have Different Disease Phenotypes and Outcomes?
Authors' conclusion
The relative order of psoriasis and PsA diagnosis does not significantly affect disease activity or radiographic progression.
Study context
- Population
- Patients with PsA from an observational cohort
- Participants
- 1,702 patients
- Exposure
- Concurrent PsA or antecedent PsA vs classical PsA
- Classical PsAn = 1,138reference
- Concurrentn = 444
- Antecedent PsAn = 120
- Outcome
- Mean disease activity (adjusted 5-year mean swollen joint count (SJC)) and course of radiographic damage (time to radiographic progression)
- Follow-up
- 5-year
Methodological detailsobservational cohort, multivariable linear regression, Cox proportional hazards regression
- Observational cohort
- Multivariable linear regression
- Cox proportional hazards regression
Main finding
As reported in the abstract
Time-averaged disease activity and time to radiographic progression
Observational data: associations, not effects.
Further findings
Psoriasis onset in antecedent PsA
- Biologic disease-modifying antirheumatic drug (bDMARD) use associated with reduced risk of developing psoriasis in antecedent PsA
- Cox regression
Original publication
Do Patients Diagnosed With Psoriatic Arthritis Before or Concurrently With Psoriasis Have Different Disease Phenotypes and Outcomes? J Rheumatol. Published 1 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →