Lupus & antiphospholipid syndrome
Distinctive clinical traits of lupus-related myocarditis: a multicentre retrospective study
Authors' conclusion
myoSLE has unique clinical traits compared with other forms of myocarditis and is associated with aB2GPI and a more severe SLE course.
Study context
- Population
- Patients with systemic lupus erythematosus (SLE)-related myocarditis from three centres, compared with consecutive patients with SLE or myocarditis alone
- Exposure
- SLE-related myocarditis vs SLE alone vs myocarditis alone
- Outcome
- Distinctive clinical traits of myoSLE
Methodological detailsmulticentre, three centres, consecutive comparator patients
- Multicentre
- Three centres
- Consecutive comparator patients
Main finding
As reported in the abstract
Women
72% vs 43%
P = 0.013
Distinctive clinical traits of myoSLE
Conduction abnormalities
22% vs 5%
P = 0.046
Distinctive clinical traits of myoSLE
Left ventricular function compromise
48% vs 30%
numerically higher
- Multivariate: myoSLE associated with anti-β-2-glycoprotein I antibodies (aB2GPI)
- P = 0.014
- Multivariate: myoSLE associated with a higher number of involved BILAG domains in patient history
- P = 0.003
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Distinctive clinical traits of lupus-related myocarditis: a multicentre retrospective study. Rheumatology (Oxford). Published 24 July 2024. doi:10.
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