Distal coronary artery abnormalities in Kawasaki disease: experience on CT coronary angiography in 176 children
Authors' conclusion
CTCA demonstrates CAAs in distal segments of coronary arteries, including branches, in a significant number of children with KD-these cannot be detected on TTE.
Study context
- Population
- Children with Kawasaki disease who underwent CT coronary angiography (CTCA), 2013–21
- Participants
- 176 children
- Exposure
- CTCA vs those on transthoracic echocardiography (TTE) for detection of distal coronary artery abnormalities (CAAs) in Kawasaki disease (KD)
- Outcome
- Detection of CAAs in distal coronary artery segments
Methodological detailsCTCA compared with TTE, 128-slice dual source CT
- CTCA compared with TTE
- 128-slice dual source CT
Main finding
As reported in the abstract
Distal CAAs on CTCA
| Group | Value | Aneurysms identified | Distal aneurysms |
|---|---|---|---|
| CTCA | 13.06% | 60 | 23 |
| TTE | 40 |
Value
CTCA13.06%
TTE— not stated in the abstract
Aneurysms identified
CTCA60
TTE40
Distal aneurysms
CTCA23
TTE— not stated in the abstract
- Isolated distal CAAs
- 4
- Proximal aneurysms with distal contiguous extension
- 11
- Non-contiguous proximal and distal aneurysms
- 9
- Distal aneurysms without proximal involvement of same artery
- 4
Observational data: associations, not effects.
Further findings
Complications (thrombosis, mural calcification, stenosis)
- Identified on CTCA, missed on TTE
Original publication
Distal coronary artery abnormalities in Kawasaki disease: experience on CT coronary angiography in 176 children. Rheumatology (Oxford). Published 8 April 2022. doi:10.
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