Novel multiple Z-score models for detection of coronary artery dilation: application in Kawasaki disease
Authors' conclusion
The Kuo Z-Score models, applicable across a broad age range, provides robust identification of coronary artery dilatation and aneurysm in KD.
Study context
- Population
- Children from newborns to 10 years old free from coronary or heart diseases
- Participants
- 1,180 children
- Outcome
- Kuo Z-Score models for LCA, LAD and RCA across five age groups (0-6, 6-7, 7-8, 8-9, 9-10 years)
Methodological detailsBox-Cox transformation for right coronary artery (RCA), Anderson-Darling normality test
- Box-Cox transformation for RCA
- Anderson-Darling normality test
Main finding
As reported in the abstract
- Only the normality test for the RCA in the 7-8 year age group failed
- The proposed model fitted to the normality assumption outperforming the other models
Observational data: associations, not effects.
Original publication
Novel multiple Z-score models for detection of coronary artery dilation: application in Kawasaki disease. Pediatr Rheumatol Online J. Published 21 December 2024. doi:10.
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