Pediatric rheumatology

Use of psychotropic medication in incident juvenile idiopathic arthritis patients from 2000 to 2014: a case-control cohort study

Clin Exp RheumatolPublished Case-control cohort study

Authors' conclusion

The use of psychotropic medication, particularly antidepressants, was more common in patients with JIA compared to comparators in the general population.

Study context

Population
Incident juvenile idiopathic arthritis (JIA) patients in Finland (index dates 2000–2014) and population comparators, followed until 31 December 2015
Participants
4,180 vs 12,512
Comparison
Incident JIA vs population controls
  • JIAn = 4,180
  • Controlsn = 12,512reference
Outcome
Purchase of psychotropic medication
Follow-up
Until 31 December 2015
Methodological detailsregister-based, three population comparators per case, generalised linear models
  • Register-based
  • Three population comparators per case
  • Generalised linear models

Main finding

As reported in the abstract

Any psychotropic drug purchased · during follow-up

P < 0.001

Observational data: associations, not effects.

Further findings

Most purchased drug class

Antidepressants were the most purchased drugs in both groups

Antidepressant use by gender in JIA (subgroup)

Females with JIA used antidepressants more often than males with JIA

Original publication

Use of psychotropic medication in incident juvenile idiopathic arthritis patients from 2000 to 2014: a case-control cohort study. Clin Exp Rheumatol. Published 28 March 2022. doi:10.55563/clinexprheumatol/26u6uu

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