Disease characteristics and medications use in idiopathic inflammatory myopathy: a multi-centre prospective observational study of decentralized remote vs. traditional clinic enrolment
Authors' conclusion
Tele-research recruitment yielded a patient cohort resembling traditionally recruited patients demographically and clinically, indicating its effectiveness for robust and diverse patient recruitment in clinical studies.
Study context
- Population
- US patients with idiopathic inflammatory myopathies (IIM)
- Participants
- 120 patients
- Exposure
- Tele-research cohort vs centre-based cohort
- Tele-research cohort (TRC)n = 82
- Centre-based cohort (CBC)n = 38reference
- Outcome
- Disease characteristics (baseline demographic and clinical variables, organ involvement, diagnostic tests results and medication use) compared between remote and clinic-recruited patients
- Follow-up
- Baseline
Methodological detailsmulticentre, decentralized remote vs traditional clinic enrolment
- Multicentre
- Decentralized remote vs traditional clinic enrolment
Main finding
As reported in the abstract
Disease characteristics, TRC vs CBC
- Comparable IIM subtype prevalence among cohorts
- P = 0.85
- TRC patients received biologics more frequently
- P < 0.001
- TRC patients received csDMARDs more frequently
- P = 0.013
Observational data: associations, not effects.
Further findings
Overall cohort characteristics · baseline
- Average age
- 55 ± 13.4
- Females
- 75%
- Caucasians
- 81%
- DM
- 41%
- PM
- 27%
- Anti-synthetase syndrome
- 23%
- Necrotizing myositis
- 9%
Original publication
Disease characteristics and medications use in idiopathic inflammatory myopathy: a multi-centre prospective observational study of decentralized remote vs. traditional clinic enrolment. Rheumatology (Oxford). Published 29 August 2024. doi:10.
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