Systemic sclerosis & Raynaud's

Digital artery reconstruction with interposition vein graft: impact on secondary Raynaud’s phenomenon

Rheumatology (Oxford)Published Retrospective cohort study

Authors' conclusion

Digital artery reconstruction using an interposition vein graft is an effective procedure for improving ischaemic pain and ulceration in patients with RP. Smoking and concomitant periarterial sympathectomy were significantly associated with recurrence.

Study context

Population
Patients with secondary RP and chronic hand ischaemia with discrete proper digital artery occlusion who underwent proper digital artery reconstruction with interposition vein graft79 digits
Participants
57 patients
Outcome
Results of surgery: resolution of ischaemic pain and ulceration
Methodological detailsretrospective chart review, per-digit analysis, multivariate Cox regression, Kaplan-Meier analysis
  • Retrospective chart review
  • Per-digit analysis
  • Multivariate Cox regression
  • Kaplan-Meier analysis

Main finding

As reported in the abstract

Resolution of ischaemic pain
97.5%
Resolution of ulceration
95.3%
Recurrence during follow-up
16 (20.3%)
Surgery had no effect
2 (2.5%)
5-year recurrence-free rate (Kaplan-Meier)
69.3%

Observational data: associations, not effects.

Further findings

Independent risk factors for recurrence (multivariate Cox regression)

Smoking and concomitant periarterial sympathectomy were significant factors associated with recurrence

Original publication

Digital artery reconstruction with interposition vein graft: impact on secondary Raynaud’s phenomenon. Rheumatology (Oxford). Published 27 September 2023. doi:10.1093/rheumatology/kead524

Composed by AI from the published abstract and checked against it. How Briefs are made →

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