Systemic sclerosis & Raynaud's
Digital artery reconstruction with interposition vein graft: impact on secondary Raynaud’s phenomenon
Authors' conclusion
Digital artery reconstruction using an interposition vein graft is an effective procedure for improving ischaemic pain and ulceration in patients with RP. Smoking and concomitant periarterial sympathectomy were significantly associated with recurrence.
Study context
- Population
- Patients with secondary RP and chronic hand ischaemia with discrete proper digital artery occlusion who underwent proper digital artery reconstruction with interposition vein graft79 digits
- Participants
- 57 patients
- Outcome
- Results of surgery: resolution of ischaemic pain and ulceration
Methodological detailsretrospective chart review, per-digit analysis, multivariate Cox regression, Kaplan-Meier analysis
- Retrospective chart review
- Per-digit analysis
- Multivariate Cox regression
- Kaplan-Meier analysis
Main finding
As reported in the abstract
- Resolution of ischaemic pain
- 97.5%
- Resolution of ulceration
- 95.3%
- Recurrence during follow-up
- 16 (20.3%)
- Surgery had no effect
- 2 (2.5%)
- 5-year recurrence-free rate (Kaplan-Meier)
- 69.3%
Observational data: associations, not effects.
Further findings
Independent risk factors for recurrence (multivariate Cox regression)
- Smoking and concomitant periarterial sympathectomy were significant factors associated with recurrence
Original publication
Digital artery reconstruction with interposition vein graft: impact on secondary Raynaud’s phenomenon. Rheumatology (Oxford). Published 27 September 2023. doi:10. 1093/ rheumatology/ kead524
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