Dietary Inflammatory Index and Magnetic Resonance Imaging–Detected Knee Structural Change and Pain: A 10.7‐Year Follow‐up Study
Authors' conclusion
A proinflammatory diet, as indicated by a higher DII score, may be associated with a greater pain score and higher risk of more severe pain trajectory over 10 years. However, inconsistent findings related to structural changes suggest a discordance between the potential impact of diet on structural damage and pain in knee OA.
Study context
- Population
- Population-based cohort (mean age 63 years, 51% female)566 completed 10.7 years
- Participants
- 1,099 participants
- Exposure
- Higher vs lower baseline energy-adjusted dietary inflammatory index (DII) scores
- Outcome
- MRI-detected knee structural changes (tibial CV, bone marrow lesions (BMLs)) and knee pain (WOMAC pain; pain trajectories)
- Follow-up
- 10.7 years
Methodological detailspopulation-based, 10.7-year follow-up
- Population-based
- 10.7-year follow-up
Main finding
As reported in the abstract
Higher E-DII score and pain score, β
0.21
95% CI 0.004–0.43
Higher E-DII score and risk of "moderate pain" vs "minimal pain" trajectory, relative risk ratio
1.19
95% CI 1.02–1.39
Mean ± SD baseline E-DII score
−0.48 ± 1.39
Observational data: associations, not effects.
Original publication
Dietary Inflammatory Index and Magnetic Resonance Imaging–Detected Knee Structural Change and Pain: A 10.7‐Year Follow‐up Study. Arthritis Care Res (Hoboken). Published 26 February 2024. doi:10.
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