Diet and the risk of rheumatoid arthritis – A systematic literature review
Authors' conclusion
There is lack of consistent evidence on the role of diet in the development of RA, partly due to differences in study quality and methodology Limited evidence suggests that some healthy eating habits may reduce the risk of RA.
Study context
- Population
- Cohort-based and case-control studies on dietary patterns, foods and food groups, macronutrients, non-alcoholic beverages and risk of developing Rheumatoid arthritis (RA)19 cohort, 8 case-control studies
- Outcome
- Diet and risk of developing RA
Methodological detailsNewcastle-Ottawa Scales quality assessment, independent selection by two examiners, 984 articles screened; 2 excluded for lacking data on timing of RA diagnosis vs dietary data collection, 1 for incorrect outcome
- Newcastle-Ottawa Scales quality assessment
- Independent selection by two examiners
- 984 articles screened; 2 excluded for lacking data on timing of RA diagnosis vs dietary data collection, 1 for incorrect outcome
Main finding
As reported in the abstract
- Studies suggested protective effects of fish, vegetables and Mediterranean-style diets; results and methods heterogenous
- Some case-control studies used unvalidated diet assessment methods
- Vast majority of cohort-based studies used validated diet assessment methods; exposure definitions varied
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Diet and the risk of rheumatoid arthritis – A systematic literature review. Semin Arthritis Rheum. Published 28 October 2022. doi:10.
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