Adherence to dietary guidelines, and the risk of developing rheumatoid arthritis: results from a nested case-control study
Authors' conclusion
Reaching the recommended intake level of dietary fibre, but not overall diet quality, was independently associated with decreased risk of RA.
Study context
- Population
- Participants in the Malmö Diet and Cancer Study cohort; diet assessed at baseline (1991–1996) by validated diet history method172 validated RA cases
- Comparison
- Adherence vs non-adherence to Swedish dietary guidelines
- RA casesn = 172
- Outcome
- Risk of developing RA by adherence to dietary guidelines (DQI)
Methodological details4 controls per case, matched for sex, year of birth and year of inclusion in the Malmö Diet and Cancer Study (MDCS), conditional logistic regression
- 4 controls per case, matched for sex, year of birth and year of inclusion in the MDCS
- Conditional logistic regression
Main finding
As reported in the abstract
Overall adherence to dietary guidelines (DQI) and risk of RA
- Overall adherence to the dietary guidelines was not associated with the risk of RA
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| Adherence to recommended fibre intake and risk of RAFibre adherencevs Fibre non-adherenceCrude | 0.60 (0.39–0.93) | |
| Adherence to recommended fibre intake and risk of RAFibre adherencevs Fibre non-adherence | 0.51 (0.29–0.90) | |
| 0.20.5125Odds ratio (log scale) |
- Adherence to recommended fibre intake and risk of RA: multivariable-adjusted (energy intake, smoking, leisure time physical activity, alcohol)
Original publication
Adherence to dietary guidelines, and the risk of developing rheumatoid arthritis: results from a nested case-control study. Rheumatology (Oxford). Published 15 May 2023. doi:10.
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