Lupus & antiphospholipid syndrome
Diagnostic pathway and treatment preferences for systemic lupus erythematosus: a physician-based discrete choice experiment
Authors' conclusion
These DCEs highlight a high degree of awareness among lupus-treating physicians, with no differences across medical specialties, of the unmet need for early diagnosis and prevention of damage accrual in SLE management.
Study context
- Population
- Clinicians involved in systemic lupus erythematosus (SLE) management (57% females, 71% rheumatologists)115 invited
- Participants
- 95 clinicians
- Outcome
- Physicians' preferences (relative importance of attributes) on diagnostic pathways and treatment priorities for SLE
Methodological detailsphysician-based, expert-board-defined profiles, Board of 11 SLE experts and a discrete choice experiment (DCE) expert statistician defined profiles
- Physician-based
- Expert-board-defined profiles
- Board of 11 SLE experts and a DCE expert statistician defined profiles
Main finding
As reported in the abstract
- Referral time to a rheumatologist, mild-moderate SLE (relative importance (RI))
- 25%
- Referral time to a rheumatologist, severe SLE (RI)
- 20%
- Effect on organ damage progression after 12 months, mild-moderate SLE (RI)
- 35%
- Effect on organ damage progression after 12 months, severe SLE (RI)
- 41%
- Reduction in disease activity levels after 6 months (max RI)
- 19%
- GC dose reduction after 6 months (max RI)
- 13%
- Prednisone <5 mg/day, mild-moderate SLE (PW)
- 66.1
- Prednisone <5 mg/day, severe SLE (PW)
- 14.2
- Administration route, action rapidity, patient-global assessment, serious infection risk (RI)
- 7-8%
Further findings
Subgroups by clinicians' areas of expertise
- No distinctions found among subgroups
Original publication
Diagnostic pathway and treatment preferences for systemic lupus erythematosus: a physician-based discrete choice experiment. Clin Exp Rheumatol. Published 7 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →