Lupus & antiphospholipid syndrome

Satisfaction and effectiveness of switching from intravenous to subcutaneous belimumab treatment in daily clinical practice

LupusPublished Observational study

Authors' conclusion

Overall satisfaction, satisfaction with via of administration, and satisfaction with the time taken to receive BEL were higher for SQ BEL treatment.

Study context

Population
Stable SLE patients (EULAR/ACR 2019) on SQ belimumab (BEL) with previous intravenous (IV) BEL, Catalonia
Participants
27 patients
Exposure
Switch from IV to SQ belimumab
  • SQ BELn = 27
Outcome
Satisfaction with SQ BEL therapy (RASQ-SQ modified for BEL)
Methodological detailsmulticentre, 7 reference centres in Catalonia
  • Multicentre
  • 7 reference centres in Catalonia

Main finding

As reported in the abstract

Satisfaction with SQ BEL

Confidence in SQ BEL

84%

SQ BEL convenient or very convenient

85.2%

Felt they had gained time with the change

85%

Would recommend SQ injection to other patients

89%

Observational data: associations, not effects.

Further findings

Disease activity (mean SLEDAI) and remission rates

Remain stable after switching

Baseline characteristics · mean baseline

Mean baseline SLEDAI (SD 2.4)
2.96
SLICC score (SD 0.88)
0.67
Median time on IV BEL before switching
21 months

Original publication

Satisfaction and effectiveness of switching from intravenous to subcutaneous belimumab treatment in daily clinical practice. Lupus. Published 6 March 2024. doi:10.1177/09612033241237560

Composed by AI from the published abstract and checked against it. How Briefs are made →

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