Lupus & antiphospholipid syndrome
Comparison of the Systemic Lupus Erythematosus (SLE) Risk Probability Index (SLE Risk Probability Index (SLERPI)) scale against the European League Against Rheumatism/American College of Rheumatology (ACR/EULAR) and Systemic Lupus International Collaborating Clinics (SLICC) criteria
Authors' conclusion
The SLERPI scale could be useful in the diagnosis of SLE, especially in early stages, given its good correlation with other classification scales and its good sensitivity.
Study context
- Population
- Colombian inpatients and outpatients diagnosed with SLE, registry of two referral hospitals in Bogotá, 2016–2019 (median age 36 years; 82.2% women)
- Participants
- 146 inpatients
- Exposure
- SLERPI vs 2019 ACR/EULAR and 2012 SLICC classification criteria
- Outcome
- Correlation between absolute scores of SLERPI, ACR/EULAR and SLICC (Spearman)
Methodological detailsregistry-based, two referral hospitals
- Registry-based
- Two referral hospitals
Main finding
As reported in the abstract
Correlation between absolute scores (Spearman)
Spearman correlation
0.76
P = 0.000
SLERPI vs ACR/EULAR · moderately strong correlation
Spearman correlation
0.80
P = 0.000
SLERPI vs SLICC · very strong correlation
Observational data: associations, not effects.
Further findings
Prevalence of SLERPI items
- ANA
- 92%
- Immunological disorders
- 71%
- Arthritis
- 64%
Most used treatments
- Corticosteroids
- 87.6%
- Chloroquine
- 67.8%
Characteristics of patients classified as SLE by SLERPI
- Higher incidence of hematological compromise and elevated serological markers such as anti-DNA antibodies; more commonly received corticosteroids and azathioprine; higher prevalence of hypertension
Original publication
Comparison of the SLE Risk Probability Index (SLERPI) scale against the European League Against Rheumatism/American College of Rheumatology (ACR/EULAR) and Systemic Lupus International Collaborating Clinics (SLICC) criteria. Lupus. Published 6 March 2024. doi:10.
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