Sjögren's disease & overlap diseases
Diagnosing a child presenting with symptoms suggesting Sjögren’s disease: a tool for clinical practice
Authors' conclusion
It performed well in an international cohort of cSjD, supporting the integration of this algorithm into clinical practice; however, its utility may be limited by low utilization of diagnostic testing in this population.
Study context
- Population
- International cohort of participants with clinician-diagnosed childhood SjD (cSjD)100 with data for ≥1 pathway
- Participants
- 300 participants
- Outcome
- Sensitivity of the cSjD diagnostic algorithm
Methodological detailsexpert consensus-developed algorithm, international cohort, Algorithm developed by CARRA Sjögren Disease Workgroup and International Childhood Sjögren Disease Workgroup experts via virtual meetings, using adult classification criteria as framework, finalized by majority rule
- Expert consensus-developed algorithm
- International cohort
- Algorithm developed by CARRA Sjögren Disease Workgroup and International Childhood Sjögren Disease Workgroup experts via virtual meetings, using adult classification criteria as framework, finalized by majority rule
Performance
As reported in the abstract
Overall sensitivity of the cSjD diagnostic algorithm
| Test or model | Sensitivity |
|---|---|
| Algorithm | 75% |
Algorithm
Sensitivity75%
Further findings
- Parotitis pathway sensitivity
- 70%
- Sicca pathway sensitivity
- 82%
- Extraglandular pathway sensitivity (lowest)
- 52%
Original publication
Diagnosing a child presenting with symptoms suggesting Sjögren’s disease: a tool for clinical practice. Rheumatology (Oxford). Published 3 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →