Systemic sclerosis & Raynaud's

Dermatoscopy limitation and the critical role of capillaroscopy in the evaluation of systemic sclerosis and Raynaud’s phenomenon among African American Veterans

Semin Arthritis RheumPublished Diagnostic accuracy study

Authors' conclusion

In conclusion, dermatoscopy resulted in a high rate of uninterpretable examinations in patients with RP, particularly among African American Veterans.

Study context

Population
United States (US) Veterans undergoing evaluation for CTD-related Raynaud's phenomenon (RP), TVHS Hospital; 28% self-identified as African American38 Veterans with RP assessed
Participants
11 vs 31
Comparison
200X dermatoscope (smartphone focus) vs 250X Smart G-Scope USB capillaroscope (automatic focus) for nailfold evaluation
  • Fitzpatrick IV–VIn = 11
  • Fitzpatrick I–IIIn = 31reference
Outcome
Interpretability (image clarity) of nailfold evaluation by skin pigmentation
Methodological detailssingle-centre, two devices, two independent expert readers
  • Single-centre
  • Two devices
  • Two independent expert readers

Performance

As reported in the abstract

Blurry images with dermatoscopy

Further findings

Interpretability with USB-capillaroscope

USB-capillaroscope improved interpretability across the entire cohort, especially in skin tones IV–VI

SD-pattern detected by USB-capillaroscope in studies uninterpretable with dermatoscope

SD-pattern detected (of 5 uninterpretable studies)
4

Original publication

Dermatoscopy limitation and the critical role of capillaroscopy in the evaluation of systemic sclerosis and Raynaud’s phenomenon among African American Veterans. Semin Arthritis Rheum. Published 5 March 2026. doi:10.1016/j.semarthrit.2026.152961

Composed by AI from the published abstract and checked against it. How Briefs are made →

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