Lupus & antiphospholipid syndrome
Current and future interventions for neonatal lupus: A review of the national library of Medicine’s clinical trials database
Authors' conclusion
Congenital heart block from NLE was decreased in recurrence by treatment with hydroxychloroquine.
Study context
- Population
- Registered clinical trials for the treatment or prevention of NLE and its cardiac manifestations, since 1994Three eligible trials
- Outcome
- Recurrence rate of CHB (one trial)
Methodological detailsClinicalTrials.gov registry search, ClinicalTrials.gov searched on January 24, 2025
- ClinicalTrials.gov registry search
- ClinicalTrials.gov searched on January 24, 2025
Pooled result
As reported in the abstract
HCQ reduced the recurrence rate of congenital heart block (CHB) by more than half
from 18% to 7.4%
Original publication
Current and future interventions for neonatal lupus: A review of the national library of Medicine’s clinical trials database. Lupus. Published 24 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →