Lupus & antiphospholipid syndrome

The conditions that patients with systemic lupus erythematosus should fulfill before pregnancy to optimize outcomes: a large-scale multicenter cohort study from China

Arthritis Res TherPublished Retrospective cohort study

Authors' conclusion

This study delineated the conditions that patients with SLE should fulfill before pregnancy

Study context

Population
Pregnant patients with systemic lupus erythematosus (SLE), multicenter Chinese SLE cohort
Participants
347 singleton pregnancies
Exposure
Patients fulfilling preconception conditions vs not fulfilling them
Outcome
Live birth
Methodological detailsmulticenter, logistic regression
  • Multicenter
  • Logistic regression

Main finding

As reported in the abstract

P = 0.004

Observational data: associations, not effects.

Further findings

OutcomeP value
Flares during pregnancyPatients who fulfilled the conditions vs OthersP = 0.009
Severe flares during pregnancyPatients who fulfilled the conditions vs OthersP = 0.011

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

The conditions that patients with systemic lupus erythematosus should fulfill before pregnancy to optimize outcomes: a large-scale multicenter cohort study from China. Arthritis Res Ther. Published 11 February 2025. doi:10.1186/s13075-025-03497-9

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.