Vasculitis & polymyalgia rheumatica
Concordance of relapse symptoms in patients with giant cell arteritis
Study context
- Population
- Patients diagnosed with giant cell arteritis (GCA)median follow-up 5.3 years
- Participants
- 510 patients
- Exposure
- C1 vs C2 vs C3 vs C4
- C1n = 286
- C2n = 110
- C3n = 114
- C4n = 510
- Outcome
- Concordance of symptoms between initial presentation, first relapse and second relapse
Methodological detailsthree cohorts and aggregate cohort, odds ratios and conditional probabilities
- Three cohorts and aggregate cohort
- Odds ratios and conditional probabilities
Main finding
As reported in the abstract
Symptom concordance at relapse
Patients relapsing with a symptom category absent at baseline
≈20%
Observational data: associations, not effects.
Further findings
At least 1 relapse; 5-year first relapse rate (all 510 patients)
- Patients with at least 1 relapse
- 303
- 5-year first relapse rate
- 66% (95% CI 60-70%)
At least 2 relapses; 5-year second relapse rate (all 510 patients)
- Patients with at least 2 relapses
- 160
- 5-year second relapse rate
- 36% (95% CI 31-41%)
Original publication
Concordance of relapse symptoms in patients with giant cell arteritis. Semin Arthritis Rheum. Published 14 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →