Vasculitis & polymyalgia rheumatica

Prognostic significance and rationality of regular non-invasive imaging follow-up in Takayasu arteritis: A large multicenter cohort study

Semin Arthritis RheumPublished Retrospective cohort study

Authors' conclusion

In the absence of clinical activity, the rate of radiological activity and/or progression is very low in patients with TAK during routine follow-up.

Study context

Population
Adult patients with TAK from 11 tertiary centres
Participants
204 patients580 imaging studies
Exposure
Regular imaging follow-up regardless of clinical activity vs others
Outcome
Radiological activity and/or progression on imaging
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

Radiological activity and/or progression
Radiological activity and/or progression in all imaging
116 (20 %) of the 580
Imaging performed while physician's global assessment (PGA) inactive
418 (72 %) of the 580
Radiological activity and/or progression in PGA inactive imaging
18 (4 %)
Younger age as predictor, OR (95% CI: 0.961-0.999), P = 0.041
0.980
Active PGA as predictor, OR (95% CI: 17.961-56.219), P < 0.001
31.766

Observational data: associations, not effects.

Further findings

Disease outcomes (MACE, VDI score, mortality)

No difference between regular imaging follow-up and others

Original publication

Prognostic significance and rationality of regular non-invasive imaging follow-up in Takayasu arteritis: A large multicenter cohort study. Semin Arthritis Rheum. Published 12 August 2025. doi:10.1016/j.semarthrit.2025.152813

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