Lupus & antiphospholipid syndrome
Comparison of two frailty definitions in women with systemic lupus erythematosus
Authors' conclusion
Frailty is present in 17.9-26.9% of women with SLE. These metrics identified a similar, but non-identical group of women as frail.
Study context
- Population
- Women aged 18–70 years with SLE
- Participants
- 67 women
- Exposure
- Fried phenotype vs SLICC Frailty Index
- Outcome
- Frailty prevalence according to each metric
Main finding
Frailty prevalence
Kappa
0.41
P < 0.01
By group
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| Association of frailty with disability (age-adjusted)FP frailvs FP non-frailAge-adjusted · After age adjustment | 4.7 (1.2–18.8) | |
| Association of frailty with disability (age-adjusted)SLICC-FI frailvs SLICC-FI non-frailAge-adjusted · After age adjustment | 4.6 (1.3–15.8) | |
| 0.050.21520Odds ratio (log scale) |
Frail vs non-frail women: disease damage, Patient Reported Outcome Measurement Information System (PROMIS) scores, disability
- Frail women had greater disease damage, worse PROMIS scores and greater disability (all P < 0.01 for Fried phenotype (FP) and SLICC Frailty Index (SLICC-FI))
Original publication
Comparison of two frailty definitions in women with systemic lupus erythematosus. Rheumatology (Oxford). Published 9 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →