Spondyloarthritis & psoriatic arthritis
Comparative analysis of disease outcomes: Early vs. late transition from psoriasis to psoriatic arthritis
Authors' conclusion
There were no significant differences in the PsA features at baseline between the two groups. However, on follow-up, there was a trend for lower cumulative disease activity but not in the rate of radiographic progression in the late transition group.
Study context
- Population
- Patients who developed psoriatic arthritis (PsA) after psoriasis, diagnosed with PsA prior to or at presentation to the clinic
- Participants
- 702 patients
- Exposure
- Late vs early transition from psoriasis to PsA
- Outcome
- Disease activity: 5-year adjusted mean swollen joint count (SJC); damage: time to radiographic progression
- Follow-up
- 5 years
Methodological detailsinception cohort (PsA duration ≤2 years), logistic regression, multivariate linear regression, Cox regression
- Inception cohort (PsA duration ≤2 years)
- Logistic regression
- Multivariate linear regression
- Cox regression
Main finding
As reported in the abstract
- Trend for lower disease activity over time in the late transition group
- Radiographic progression not significantly different
Observational data: associations, not effects.
Further findings
Baseline features of late transition
- Younger age at psoriasis diagnosis and older age at PsA diagnosis in late transition
- Higher BMI and PASI and less frequent csDMARD use at baseline in late transition
Original publication
Comparative analysis of disease outcomes: Early vs. late transition from psoriasis to psoriatic arthritis. Semin Arthritis Rheum. Published 30 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →