Lupus & antiphospholipid syndrome

Clustering of systemic lupus erythematosus mortality in southwestern Spain

LupusPublished Ecological study

Main finding · SLE average ASMR for the periodResult — go to the resultSex ratio (female/male) 3.8

Authors' conclusion

We detected a cluster of provinces with an excess risk of female SLE mortality in the southwest of Spain.

Study context

Population
Deaths registered in Systemic Lupus Erythematosus (SLE) at the Spanish National Institute of Statistics, 2001–2020
Comparison
SLE mortality across Spanish provinces, women vs men
Outcome
Time trends and provincial clustering of SLE mortality
Follow-up
2001-2020
Methodological detailsJointpoint regression, spatial analysis: Global Moran I, local indicators of spatial association (LISA), Kulldorff's spatial scan statistic
  • Jointpoint regression
  • Spatial analysis: Global Moran I, LISA, Kulldorff's spatial scan statistic

Main finding

SLE average ASMR for the period

Sex ratio (female/male)

3.8

By group

Women

2.7

Men

0.7

As reported in the abstract

In women, provinces with RR>1 with posterior probabilities (PP) greater than 0.8 (Seville, Cadiz, Huelva, Murcia, Barcelona, Zaragoza, Huesca, Leon)
8

Original publication

Clustering of systemic lupus erythematosus mortality in southwestern Spain. Lupus. Published 28 August 2023. doi:10.1177/09612033231199511

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