Osteoarthritis

Clinically Relevant Subgroups Among Athletes Who Have Ruptured Their Anterior Cruciate Ligaments: A Delaware‐Oslo Cohort Study

Arthritis Care Res (Hoboken)Published Prospective cohort study

Authors' conclusion

The prevalence of OA in all subgroups is highly concerning.

Study context

Population
Individuals with anterior cruciate ligament (ACL) rupture enrolled after resolution of effusion, pain and range of motion impairments and with quadriceps strength ≥70% of the uninvolved limb (45.7% male, mean age 26.2 years)
Participants
293 individuals
Exposure
Latent subgroups after ACL rupture
Outcome
Radiographic osteoarthritis (OA) (Kellgren/Lawrence grade ≥1) in the involved knee
Follow-up
5 years after injury
Methodological detailsmixture modeling (latent subgroups, probabilistic assignment), chi-square tests
  • Mixture modeling (latent subgroups, probabilistic assignment)
  • Chi-square tests

Main finding

As reported in the abstract

Radiographic OA in the involved knee · 5 years

P = 0.059

Observational data: associations, not effects.

Original publication

Clinically Relevant Subgroups Among Athletes Who Have Ruptured Their Anterior Cruciate Ligaments: A Delaware‐Oslo Cohort Study. Arthritis Care Res (Hoboken). Published 1 March 2023. doi:10.1002/acr.25089

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