Clinical manifestations, treatment and prognosis of juvenile idiopathic arthritis with pulmonary involvement in China: a single centre study
Authors' conclusion
Patients with JIA with pulmonary involvement present with early onset, high mortality rate.
Study context
- Population
- Patients with juvenile idiopathic arthritis (JIA) with pulmonary involvement, China5.03% of JIA patients
- Participants
- 60 patients
- Outcome
- Pulmonary involvement in JIA (prevalence) and its clinical characteristics
Methodological detailssingle-centre, Treated with NSAIDs, along with GCs, DMARDs and biological agents
- Single-centre
- Treated with NSAIDs, along with GCs, DMARDs and biological agents
Main finding
As reported in the abstract
- JIA patients with pulmonary involvement
- 60 (5.03%)
- Systemic JIA (sJIA) subtype
- 63.3%
- Rheumatoid factor (RF)-positive polyarthritis (pJIA) subtype
- 25.0%
- Macrophage activation syndrome incidence
- 21.6%
- Interstitial lung disease (ILD) as diagnosis
- 90%
- Initial respiratory symptoms/signs
- 61.7%
- Respiratory support required
- 21.7%
- Survival at 1 year
- ≈93.3%
- Survival at 5 years
- 90.0%
Observational data: associations, not effects.
Original publication
Clinical manifestations, treatment and prognosis of juvenile idiopathic arthritis with pulmonary involvement in China: a single centre study. Clin Exp Rheumatol. Published 19 February 2024. doi:10.
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