Lupus & antiphospholipid syndrome
Chronic abdominal aortic occlusive disease related to antiphospholipid syndrome: a rare presentation
Authors' conclusion
The study shed light on the rare occurrence of CAAOD in APS, highlighting the roles of smoking and hyperhomocysteinaemia as notable risk factors.
Study context
- Population
- aPL-positive patients with arterial thrombotic events, 2013 to 2021
- Participants
- 114 patients
- Comparison
- Chronic abdominal aortic occlusive disease (CAAOD) vs non-CAAOD in aPL-positive patients with arterial thrombotic events
- CAAODn = 12
Main finding
As reported in the abstract
- CAAOD found in 12 of 114 aPL-positive patients with arterial events
Observational data: associations, not effects.
Further findings
Critical smoking habits
P = 0.006
Hyperhomocysteinaemia
P = 0.026
- CAAOD characteristics: age and male sex
- 36.67 · ± 11.83
Radiology in CAAOD
- Long-segment infrarenal aorta stenosis, occasionally involving renal and common iliac arteries; from smooth lumen narrowing to total occlusion
Treatment
- Interventions or surgery, complementing anticoagulation
Original publication
Chronic abdominal aortic occlusive disease related to antiphospholipid syndrome: a rare presentation. RMD Open. Published 4 January 2024. doi:10.
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