Choroidal vascularity analysis in patients with juvenile idiopathic arthritis without acute uveitis
Authors' conclusion
In the absence of active uveitis, choroidal thickness and vascularity are not significantly different in JIA patients and HC.
Study context
- Population
- Patients with juvenile idiopathic arthritis (JIA) without clinical signs of active uveitis and age-matched healthy controls
- Participants
- 21 vs 22
- Exposure
- JIA without active uveitis vs healthy controls
- JIAn = 21
- Healthy controls (HC)n = 22reference
- Outcome
- Choroidal thickness (subfoveal choroidal thickness (SCT), nasal choroidal thickness (NCT), temporal choroidal thickness (TCT)), choroidal area (TCA, LA, SA) and choroidal vascular index (CVI) on EDI-OCT; anterior chamber inflammation by laser flare meter
Methodological detailscase-control, enhanced-depth imaging optical coherence tomography (EDI-OCT) image binarisation
- Case-control
- EDI-OCT image binarisation
Main finding
As reported in the abstract
Choroidal thickness, area and vascularity
- No statistically significant difference in choroidal area (TCA, luminal area (LA) and stromal area (SA)) between JIA and HC
- JIA vs HC: P = 0.274
- JIA vs HC: P = 0.568
- JIA vs HC: P = 0.430
- JIA vs HC: P = 0.166
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Anterior chamber inflammation (laser flare meter)Statistically significant difference | P = 0.002 |
Original publication
Choroidal vascularity analysis in patients with juvenile idiopathic arthritis without acute uveitis. Clin Exp Rheumatol. Published 29 February 2024. doi:10. 55563/ clinexprheumatol/ nddba1
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