Pediatric rheumatology

Choroidal vascularity analysis in patients with juvenile idiopathic arthritis without acute uveitis

Clin Exp RheumatolPublished Cross-sectional study

Authors' conclusion

In the absence of active uveitis, choroidal thickness and vascularity are not significantly different in JIA patients and HC.

Study context

Population
Patients with juvenile idiopathic arthritis (JIA) without clinical signs of active uveitis and age-matched healthy controls
Participants
21 vs 22
Exposure
JIA without active uveitis vs healthy controls
  • JIAn = 21
  • Healthy controls (HC)n = 22reference
Outcome
Choroidal thickness (subfoveal choroidal thickness (SCT), nasal choroidal thickness (NCT), temporal choroidal thickness (TCT)), choroidal area (TCA, LA, SA) and choroidal vascular index (CVI) on EDI-OCT; anterior chamber inflammation by laser flare meter
Methodological detailscase-control, enhanced-depth imaging optical coherence tomography (EDI-OCT) image binarisation
  • Case-control
  • EDI-OCT image binarisation

Main finding

As reported in the abstract

Choroidal thickness, area and vascularity
  • No statistically significant difference in choroidal area (TCA, luminal area (LA) and stromal area (SA)) between JIA and HC
  • JIA vs HC: P = 0.274
  • JIA vs HC: P = 0.568
  • JIA vs HC: P = 0.430
  • JIA vs HC: P = 0.166

Observational data: associations, not effects.

Further findings

OutcomeP value
Anterior chamber inflammation (laser flare meter)Statistically significant differenceP = 0.002

Original publication

Choroidal vascularity analysis in patients with juvenile idiopathic arthritis without acute uveitis. Clin Exp Rheumatol. Published 29 February 2024. doi:10.55563/clinexprheumatol/nddba1

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.