Lupus & antiphospholipid syndrome
Causes of Death Among Individuals With Systemic Lupus Erythematosus by Race and Ethnicity: A Population‐Based Study
Main finding · Causes of deathResult — go to the resultAge-standardized mortality ratio, CVD as underlying cause of death 3.63Authors' conclusion
Individuals with SLE experience a disproportionate burden of CVD mortality compared to the general population, which is magnified for Asian and Hispanic groups.
Study context
- Population
- Systemic lupus erythematosus (SLE) cases among residents of San Francisco County, CA (California Lupus Surveillance Project), January 1, 2007 to December 31, 2009135 deaths
- Participants
- 812 residents
- Exposure
- SLE cases vs the corresponding general population; causes of death by race, ethnicity and sex
- SLEn = 812
- Outcome
- Specific causes of death by race and ethnicity
- Follow-up
- 10-year period
Methodological detailsmatched to the National Death Index over a 10-year period, logistic regression, age-adjusted, age-standardized mortality ratios
- Matched to the National Death Index over a 10-year period
- Logistic regression, age-adjusted
- Age-standardized mortality ratios
Main finding
Causes of death
Age-standardized mortality ratio, cardiovascular disease (CVD) as underlying cause of death
3.63
As reported in the abstract
- CVD, leading cause of death overall and across all racial and ethnic groups
- 33%
- Rheumatic disease
- 18%
- Hematologic/oncologic conditions
- 18%
Observational data: associations, not effects.
Further findings
Deaths recorded and age at death · 10-year follow-up
- Deaths
- 135
- Mean ± SD age at death (years)
- 62.2 ± 15.6
Leading causes of death after CVD
- Rheumatic disease
- 18%
- Hematologic/oncologic conditions
- 18%
CVD deaths by race/ethnicity, SLE vs general population
- Asian individuals with SLE vs general population
- nearly 4 times higher
- Hispanic individuals with SLE vs general population
- 6 times higher
Original publication
Causes of Death Among Individuals With Systemic Lupus Erythematosus by Race and Ethnicity: A Population‐Based Study. Arthritis Care Res (Hoboken). Published 15 September 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →