Spondyloarthritis & psoriatic arthritis

Cardiovascular comorbidities in psoriatic arthritis: epidemiology and risk factors in two different European populations

Clin Exp RheumatolPublished Cross-sectional study

Authors' conclusion

The prevalence of AH, T2D and CV diseases were higher in Italian patients rather than Belgians. Moreover, among patients with PsA, the risk of AH was higher in the Italian cohort compared to the Belgian cohort.

Study context

Population
Adults (≥18 years) with psoriatic arthritis (PsA) fulfilling CASPAR criteria, Belgium and Italy
Participants
803 adults
Exposure
Italian vs Belgian PsA patients
  • Italiann = 340
  • Belgiann = 463reference
Outcome
Prevalence of CV comorbidities
Methodological detailscross-sectional analysis of two longitudinal cohorts
  • Cross-sectional analysis of two longitudinal cohorts

Main finding

As reported in the abstract

Prevalence of arterial hypertension (AH)

Observational data: associations, not effects.

Further findings

Prevalence of type 2 diabetes (T2D)

Prevalence of CV diseases (MI, stroke or TIA)

Prevalence of obesity (BMI ≥30)

Prevalence of dyslipidaemia (Italy only) / hypercholesterolaemia (Belgium only)

OutcomeORP value
Risk of AH, adjusted (age, sex, smoking, PsA duration, other CV comorbidities, therapy, disease activity, function)2.00P = 0.007
  • Prevalence of dyslipidaemia (Italy only) / hypercholesterolaemia (Belgium only): lipid profile not comparable between the two groups, due to the different way of collection

Risk of arterial hypertension (AH), adjusted (age, sex, smoking, PsA duration, other cardiovascular (CV) comorbidities, therapy, disease activity, function)

Country not a predictor for risk of T2D and CV diseases

Prevalence of obesity (BMI ≥30)

Obesity prevalence not different between the two groups

Original publication

Cardiovascular comorbidities in psoriatic arthritis: epidemiology and risk factors in two different European populations. Clin Exp Rheumatol. Published 10 October 2022. doi:10.55563/clinexprheumatol/aovika

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