Vasculitis & polymyalgia rheumatica

Burden, Causes, and Outcomes of Hospitalization in Patients With Giant Cell Arteritis: A US National Cohort Study

Arthritis Care Res (Hoboken)Published Retrospective cohort study

Authors' conclusion

GCA patients frequently experience unplanned health care utilization, with 1 in 3 patients experiencing readmission within 6 months, and 3% dying within the follow-up period. Infection and CVDs are common causes of readmission and may be related to glucocorticoid exposure.

Study context

Population
Adults ≥50 years hospitalized with giant cell arteritis (GCA) between January and June 2017, 2017 US National Readmission Database, with at least 6 months of follow-up70% women, median age 77 years
Participants
1,206 adults
Outcome
Burden of hospitalization: 6-month risk of readmission, total days spent in hospital, and costs, annually
Follow-up
6 months
Methodological detailsUS national cohort, binomial logistic regression
  • US national cohort
  • Binomial logistic regression

Main finding

As reported in the abstract

Readmitted within 6 months
34%
Readmissions primarily for infections
23%
Readmissions primarily for cardiovascular diseases (CVDs)
15%
Died on follow-up
3%
Days/year in hospital, median (IQR 3-11)
5
Days/year in hospital, top quartile, median (IQR 14-26)
19

Observational data: associations, not effects.

Further findings

Patients with GCA-related ophthalmologic complications at index admission
13%

Original publication

Burden, Causes, and Outcomes of Hospitalization in Patients With Giant Cell Arteritis: A US National Cohort Study. Arthritis Care Res (Hoboken). Published 28 February 2023. doi:10.1002/acr.25081

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