Osteoarthritis

Automatic knee osteoarthritis severity grading based on X-ray images using a hierarchical classification method

Arthritis Res TherPublished Retrospective diagnostic accuracy study

Authors' conclusion

The hierarchical classification method developed in the current study is a feasible approach to assess the severity of KOA.

Study context

Population
Patients with knee X-ray images assessed for knee osteoarthritis (KOA) severity (Kellgren-Lawrence (KL) grade 0–4)
Participants
4,074 patients
Outcome
Accuracy of the hierarchical classification method for automatic KL grading of KOA severity
Methodological detailshierarchical classification method, four U-Net segmentation models, geometric, radiomic and combined models, strict decision strategy in testing cohort
  • Hierarchical classification method
  • Four U-Net segmentation models
  • Geometric, radiomic and combined models
  • Strict decision strategy in testing cohort

Performance

As reported in the abstract

Accuracy of hierarchical classification method, all X-ray images of testing cohort

Accuracy of the hierarchical classification method

65.98%

Further findings

Combined model accuracy by sub-task classification

KL grade 0-2 vs KL grade 3-4
98.50%
KL grade 3 vs KL grade 4
81.65%
KL grade 0 vs KL grade 1-2
82.07%
KL grade 1 vs KL grade 2
74.10%
  • Combined models achieved the best performance in KL grading

U-Net segmentation, dice similarity coefficient

Total joint space (TJS)
0.88
Lateral joint space (LJS)
0.86
Medial joint space (MJS)
0.88
Osteophytes
0.64

Original publication

Automatic knee osteoarthritis severity grading based on X-ray images using a hierarchical classification method. Arthritis Res Ther. Published 18 November 2024. doi:10.1186/s13075-024-03416-4

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