Associations between new obesity indices and abnormal bone density in type 2 diabetes mellitus patients
Authors' conclusion
Compared with other obesity indicators, such as BMI and WWI, the WWR has a stronger discriminative ability for T2DM patients with abnormal bone density.
Study context
- Population
- Patients with T2DM
- Participants
- 528 patients
- Exposure
- Obesity indices across bone mineral density (BMD) categories
- Outcome
- Discrimination of abnormal BMD by obesity indices (WWR, WWI, BMI)
Methodological detailslogistic regression, ROC analysis
- Logistic regression
- ROC analysis
Main finding
As reported in the abstract
AUC of WWR for predicting abnormal bone mass
- AUC, waist-weight ratio (WWR)
- 0.806
- 95% CI
- 0.770-0.843
- P
- P < 0.001
Observational data: associations, not effects.
Further findings
Obesity indices, osteopenia and osteoporosis vs normal BMD
- WWR and WWI significantly greater, body mass index (BMI) significantly lower in osteopenia and osteoporosis vs normal BMD
- P < 0.05
Independent association with abnormal BMD (logistic regression)
- WWR, WWI and BMI independently correlated with abnormal BMD
- P < 0.05
Correlation with BMD T-value
- WWR and WWI negatively correlated, BMI positively correlated with BMD T-value at various sites
- P < 0.05
Original publication
Associations between new obesity indices and abnormal bone density in type 2 diabetes mellitus patients. Osteoporos Int. Published 5 July 2024. doi:10.
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