Association of walking with incident knee osteoarthritis: a prospective cohort study using data from the UK Biobank
Authors' conclusion
More daily purposeful walking steps were associated with lower incident SKOA
Study context
- Population
- UK Biobank participants with valid accelerometer data at baseline and no history of symptomatic knee osteoarthritis (SKOA)2,711 incident SKOA
- Participants
- 89,969 participants
- Exposure
- Categories of daily purposeful walking steps vs <4000 steps/d
- Outcome
- Incident symptomatic knee OA (SKOA)
Methodological detailspopulation-based, UK Biobank, accelerometer data, Cox proportional hazard model, restricted cubic spline regression
- Population-based
- UK Biobank
- Accelerometer data
- Cox proportional hazard model
- Restricted cubic spline regression
Main finding
As reported in the abstract
Incident SKOA by daily purposeful walking steps · mean follow-up 6.85 (SD, 1.14) years
Each group vs <4000 steps/dHazard ratio (95% CI)
4000 to 5999 steps/d
0.84(0.76–0.92)
6000 to 7999 steps/d
0.81(0.71–0.90)
≥8000 steps/d
0.74(0.64–0.85)
Observational data: associations, not effects.
Further findings
Incident SKOA by daily unintentional walking steps (cadence <60 steps/min)
- More daily unintentional walking steps significantly associated with higher incident SKOA
Incident SKOA by total daily steps
- No significant association
Original publication
Association of walking with incident knee osteoarthritis: a prospective cohort study using data from the UK Biobank. Ann Rheum Dis. Published 30 January 2025. doi:10.
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