Association of Sleep Disturbance With Catastrophizing and Knee Pain: Data From the Osteoarthritis Initiative
Authors' conclusion
Sleep disturbance was associated with the presence and risk of catastrophizing and knee pain.
Study context
- Population
- Middle-aged and older individuals in the Osteoarthritis Initiative cohort (mean 64.9 years, 58% female)
- Participants
- 3,813 participants
- Exposure
- Worse vs less sleep disturbance
- Outcome
- Presence and risk of knee pain (WOMAC pain ≥5, range 0-20) and catastrophizing (Coping Strategies Questionnaire score ≥3, range 0-6) by sleep disturbance
Methodological detailssecondary analysis of the Osteoarthritis Initiative cohort, longitudinal, annual assessments, months 48 to 96 (month 48 as baseline), mediation analysis
- Secondary analysis of the Osteoarthritis Initiative cohort
- Longitudinal
- Annual assessments, months 48 to 96 (month 48 as baseline)
- Mediation analysis
Main finding
As reported in the abstract
- Prevalence of catastrophizing at baseline
- 346 (10%)
- Prevalence of knee pain at baseline
- 917 (24%)
- Knee pain with worse sleep disturbance, PR (P for trend <0.001)
- 1.4-2.0
- Catastrophizing with worse sleep disturbance, PR (P for trend <0.001)
- 1.4-3.1
- Risk of knee pain during follow-up by baseline sleep disturbance, RR (P for trend <0.001)
- 1.1
- Risk of catastrophizing during follow-up by baseline sleep disturbance, RR (P for trend <0.001)
- 1.2-1.7
Observational data: associations, not effects.
Further findings
Interactions between sleep disturbance and knee pain or catastrophizing
- No statistically significant interactions
Mediation
- Knee pain and catastrophizing mediated the sleep-catastrophizing and sleep-pain association, respectively, at baseline
- Knee pain negatively mediated the sleep-catastrophizing association longitudinally
Original publication
Association of Sleep Disturbance With Catastrophizing and Knee Pain: Data From the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). Published 6 May 2023. doi:10.
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