Association of platelet level and white blood cell level with coronary artery lesions persistence among patients with Kawasaki disease
Authors' conclusion
A high PLT level (≥450 × 10^9/L) is independently associated with CAL persistence at one month in KD patients with pre-IVIG CALs. The coexistence of high PLT and high WBC level may be associated with increased odds of CALs persistence at one month, requiring confirmation in larger prospective studies.
Study context
- Population
- Kawasaki disease (KD) patients with coronary artery lesions (CALs) prior to intravenous immunoglobulin (IVIG) treatmentKD patients with CALs prior to IVIG treatment
- Participants
- 170 patients
- Comparison
- Platelet (PLT) level and their interaction with WBC level on CALs persistence
- Outcome
- CAL persistence
- Follow-up
- One month
Methodological detailslogistic regression
- Logistic regression
Main finding
As reported in the abstract
Patients with CAL persistence
74
43.5%
Further findings
CAL persistence, PLT ≥450 × 10^9/L · one month
- Adjusted OR, PLT ≥450 × 10^9/L (comparator not stated)
- 4.860 (95% CI: 1.278, 18.487)
- Increased odds of CAL persistence
Interaction between PLT and WBC level
- Interaction P
- P = 0.049
- Nominally significant
CAL persistence, PLT ≥450 × 10^9/L and WBC >15 × 10^9/L (exploratory) · one month
- Adjusted OR (comparator not stated)
- 6.101 (95% CI: 0.620, 60.012)
- Exploratory analysis
Original publication
Association of platelet level and white blood cell level with coronary artery lesions persistence among patients with Kawasaki disease. Rheumatology (Oxford). Published 3 November 2026. doi:10.
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