Assessing Bleeding Symptoms in Pediatric Patients With Generalized Joint Hypermobility
Authors' conclusion
In a cohort of pediatric patients with GJH, three-fourths of participants had abnormal bleeding scores, with the mean bleeding score significantly elevated compared to healthy controls.
Study context
- Population
- Patients with generalized/benign joint hypermobility (GJH) ages 6–21 years seen by the rheumatology department at Nationwide Children's Hospital, Columbus, Ohio (median age 13 years)
- Participants
- 81 patients
- Exposure
- Pediatric patients with GJH vs healthy historical pediatric controls
- GJHn = 81
- Outcome
- Bleeding score (ISTH Bleeding Assessment Tool); scores of ≥3 associated with an underlying bleeding disorder
Methodological detailssingle-centre, comparison with healthy historical pediatric controls
- Single-centre
- Comparison with healthy historical pediatric controls
Main finding
As reported in the abstract
ISTH-BAT bleeding score
Mean bleeding score
5.2
Median bleeding score
4
Abnormal bleeding score
75%
95% CI 64–84
Observational data: associations, not effects.
Further findings
Commonly observed bleeding symptoms
- Oral bleeding
- 74%
- Easy bruising
- 59%
- Bleeding with minor wounds
- 42%
Previously assessed by hematology for bleeding symptoms
- Previously assessed by hematology
- 12.3%
Correlation of Beighton score with bleeding score
- Higher Beighton scores not associated with higher bleeding scores (Spearman's correlation)
- −0.08
Original publication
Assessing Bleeding Symptoms in Pediatric Patients With Generalized Joint Hypermobility. Arthritis Care Res (Hoboken). Published 18 February 2023. doi:10.
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