Sjögren's disease & overlap diseases
Are ultrasound salivary parenchymal lesions more severe in primary Sjögren patients with a longer disease duration? A cross-sectional study
Authors' conclusion
pSD duration was associated with the presence of hyperechoic bands, but not with hypoechoic areas, suggesting a progressive fibro-adipose evolution.
Study context
- Population
- Patients with primary Sjögren's disease (pSD) per 2002 or 2016 ACR/EULAR classification criteriaconsecutively included
- Participants
- 247 patients
- Exposure
- Disease duration groups from onset of buccal dryness
- Outcome
- Severity of salivary gland ultrasound (SGUS) parenchymal abnormalities (OMERACT semiquantitative score) in relation to pSD duration
Methodological detailsinternational, multicentre, Included May 2019 to February 2022
- International
- Multicentre
- Included May 2019 to February 2022
Main finding
As reported in the abstract
Pathological OMERACT score (score 2 or 3)
OR for 5-year pSD duration
1.23
95% CI 1.04; 1.47P = 0.038
Observational data: associations, not effects.
Further findings
Hyperechoic bands (25% or more)
- OR for 5-year pSD duration
- 1.18 [95% CI 1.03; 1.36], P = 0.038
- Independent of an older age
- Only US item statistically associated with pSD duration
Original publication
Are ultrasound salivary parenchymal lesions more severe in primary Sjögren patients with a longer disease duration? A cross-sectional study. Rheumatology (Oxford). Published 19 December 2024. doi:10.
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