Vasculitis & polymyalgia rheumatica
Application of the 2022 ACR/EULAR criteria for microscopic polyangiitis to patients with previously diagnosed microscopic polyangiitis
Authors' conclusion
In the new criteria, excessively high score was assigned to MPO-ANCA (or P-ANCA) and MPA-specific histopathological findings were not considered.
Study context
- Population
- Patients with previously diagnosed microscopic polyangiitis (MPA) as per the 2007 EMA algorithm and the 2012 CHCC definitionsmedian age 64.0 years
- Participants
- 117 patients
- Exposure
- 2022 ACR/EULAR criteria for MPA vs 2007 EMA algorithm and 2012 CHCC definitions
- Outcome
- Concordance rate between the new and old criteria
Main finding
As reported in the abstract
Concordance rate
96.6%
Previously diagnosed MPA unclassified by new criteria
4
Observational data: associations, not effects.
Further findings
Patients without MPO-ANCA (or P-ANCA) not reclassified as MPA despite histopathology suggestive of MPA
- Not reclassified as MPA (of 4 unclassified)
- 3
Patients with both MPO-ANCA (or P-ANCA) and PR3-ANCA (or C-ANCA) reclassified as both MPA and granulomatosis with polyangiitis (GPA)
- Reclassified as both MPA and GPA (of four)
- 3
Original publication
Application of the 2022 ACR/EULAR criteria for microscopic polyangiitis to patients with previously diagnosed microscopic polyangiitis. Clin Exp Rheumatol. Published 21 February 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →