Age at diagnosis as a prognostic factor in selected categories of juvenile idiopathic arthritis
Authors' conclusion
Age at diagnosis in the oligoarthritis was inversely and in the seronegative polyarthritis positively associated with long-term remission in JIA, primarily in females.
Study context
- Population
- Patients from the Nordic juvenile idiopathic arthritis (JIA) cohort study with oligoarthritis, seronegative polyarthritis or others (enthesitis-related, psoriatic and undifferentiated arthritis)Nordic JIA cohort
- Participants
- 358 patients
- Exposure
- Age at diagnosis within JIA categories
- Outcome
- Long-term remission
- Follow-up
- 17.5 years after diagnosis
Methodological detailsmulticentre, age at diagnosis analysed continuously
- Multicentre
- Age at diagnosis analysed continuously
Main finding
As reported in the abstract
- Oligoarthritis: predictors of remission were age at diagnosis, male gender, JADAS71 and absence of uveitis
- Seronegative polyarthritis: predictors of remission were age at diagnosis and JADAS71 score
- Oligoarthritis: remission rates highest in both genders when diagnosed <3 years of age
- Seronegative polyarthritis: highest remission with diagnosis <3 years not true for females
Observational data: associations, not effects.
Further findings
Health-related quality of life (HRQoL) and functional ability · 17.5 years after diagnosis
- Age at diagnosis had no significant effect on HRQoL or functional ability
Diagnosed before age six
- Majority of oligoarthritis and polyarthritis patients vs 29% of others
Original publication
Age at diagnosis as a prognostic factor in selected categories of juvenile idiopathic arthritis. RMD Open. Published 10 June 2025. doi:10.
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